The 1981 Caesars Palace Grand Prix was confined to a specially designed 2.2-mile, 14-turn track, in the parking lot of Caesars Palace resort.
Round 14 of the 1981 FIA Formula One World Championship returned to the Circuit Île Notre-Dame for the XX Grand Prix du Canada.
Round 13 of the 1981 FIA Formula One World Championship returned to the Autodromo Nazionale di Monza for the LII Gran Premio d'Italia.
Round 12 of the 1981 FIA Formula One World Championship returned to the Circuit Zandvoort for the XXVIII Grote Prijs van Nederland.
Round 11 of the 1981 FIA Formula One World Championship returned to the Österreichring for the XIX Großer Preis von Osterreich.
Round 10 of the 1981 FIA Formula One World Championship returned to the Hockenheimring for the XLIII Großer Preis von Deutschland.
Round 9 of the 1981 FIA Formula One World Championship returned to the Silverstone Circuit for the XXXIV Marlboro British Grand Prix.
Round 8 of the 1981 FIA Formula One World Championship returned to the Dijon-Prenois for the 67e Grand Prix de France.
Round 7 of the 1981 FIA Formula One World Championship returned to the Circuito del Jarama for the XXVII Gran Premio de España.
Round 6 of the 1981 FIA Formula One World Championship returned to the Circuit de Monaco for the XXXIX Grand Prix Automobile de Monaco.